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In the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS), treatment of men and women with average TC and LDL-C levels and below-average HDL-C levels with lovastatin (20-40 mg) reduced LDL-C by 25% and raised HDL-C 6%, resulting in a 37% reduction in the risk for the first major acute coronary event (724)

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